{"id":9517,"date":"2020-11-16T14:12:39","date_gmt":"2020-11-16T14:12:39","guid":{"rendered":"https:\/\/dermatly.com\/patologia-de-la-papilomatosis-erosiva-del-pezon\/"},"modified":"2026-03-10T16:18:03","modified_gmt":"2026-03-10T16:18:03","slug":"pathology-of-erosive-papillomatosis-of-the-nipple","status":"publish","type":"glossary","link":"https:\/\/dermatly.com\/en\/patologia-de-la-papilomatosis-erosiva-del-pezon\/","title":{"rendered":"Pathology of Erosive Nipple Papillomatosis."},"content":{"rendered":"<section class=\"textBlock\">\n<h1>Introduction to Erosive Papillomatosis of the Nipple<\/h1>\n<p>This condition, also known as florid nipple, papillary papillomatosis, or papillary adenoma, manifests as erythema or nodules on the nipple. Visually, it can be confused with mammary Paget's disease, which requires correct diagnostic differentiation.<\/p>\n<h2>Detailed Histology of Erosive Papillomatosis of the Nipple and Papillary Adenoma<\/h2>\n<p>Histological analysis of erosive papillomatosis of the nipple reveals a papillary epithelial proliferation that connects with the overlying epidermis (Figure 1). The lesion is structurally composed of fibrovascular cores that are lined by cells with a bland appearance (Figure 2).<\/p>\n<p>Characteristically, these cells usually present at least two layers thick, composed of a myoepithelial layer and an epithelial layer. These layers frequently show apocrine differentiation (Figure 3).<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h3 class=\"colour--primary\">Pathological Findings of Erosive Papillomatosis of the Nipple<\/h3>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n                <img decoding=\"async\" src=\"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/nipple-adenoma-1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd.jpg\" alt=\"Micrograph showing the papillary epithelial proliferation characteristic of erosive papillomatosis of the nipple.\">\n            <\/div>\n<p class=\"p-small\">Figure 1<\/p>\n<div class=\"imageLinkBlock__item__image\">\n                <img decoding=\"async\" src=\"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/nipple-adenoma-2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd.jpg\" alt=\"Structure of fibrovascular cores and cellular lining in the papillary lesion.\">\n            <\/div>\n<p class=\"p-small\">Figure 2<\/p>\n<div class=\"imageLinkBlock__item__image\">\n                <img decoding=\"async\" src=\"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/nipple-adenoma-3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd.jpg\" alt=\"Detail of the myoepithelial and epithelial cell layers with apocrine differentiation.\">\n            <\/div>\n<p class=\"p-small\">Figure 4<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\"><\/div>\n<h2>Clinical Investigation and Special Studies<\/h2>\n<p>Generally, specific complementary studies are not required to confirm the diagnosis of erosive papillomatosis of the nipple once the biopsy for histopathological study has been performed.<\/p>\n<h2>Crucial Differential Diagnosis<\/h2>\n<p>It is essential to differentiate erosive papillomatosis of the nipple from other malignant entities, especially carcinoma. Breast carcinoma infiltrating the nipple will exhibit much more marked nuclear atypia. Furthermore, malignant neoplasms typically lack the organized papillary growth pattern and, crucially, do not present the double lining composed of myoepithelial and epithelial cells that characterizes benign lesions.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Introducci\u00f3n a la Papilomatosis Erosiva del Pez\u00f3n Esta condici\u00f3n, tambi\u00e9n conocida como pez\u00f3n florido, papilomatosis papilar, o adenoma papilar, se manifiesta como eritema o n\u00f3dulos en el pez\u00f3n. Visualmente, puede llegar a confundirse con la enfermedad de Paget mamaria, lo que requiere una correcta diferenciaci\u00f3n diagn\u00f3stica. Histolog\u00eda Detallada de la Papilomatosis Erosiva del Pez\u00f3n y [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9521,"parent":0,"template":"","glossary-cat":[],"class_list":["post-9517","glossary","type-glossary","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.2 (Yoast SEO v27.1.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Patolog\u00eda de la papilomatosis erosiva del pez\u00f3n. - Dermatly.com - El sitio de tu piel<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dermatly.com\/en\/pathology-of-erosive-papillomatosis-of-the-nipple\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Patolog\u00eda de la papilomatosis erosiva del pez\u00f3n.\" \/>\n<meta property=\"og:description\" content=\"Introducci\u00f3n a la Papilomatosis Erosiva del Pez\u00f3n Esta condici\u00f3n, tambi\u00e9n conocida como pez\u00f3n florido, papilomatosis papilar, o adenoma papilar, se manifiesta como eritema o n\u00f3dulos en el pez\u00f3n. Visualmente, puede llegar a confundirse con la enfermedad de Paget mamaria, lo que requiere una correcta diferenciaci\u00f3n diagn\u00f3stica. 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Visualmente, puede llegar a confundirse con la enfermedad de Paget mamaria, lo que requiere una correcta diferenciaci\u00f3n diagn\u00f3stica. 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