{"id":9184,"date":"2020-11-16T01:14:41","date_gmt":"2020-11-16T01:14:41","guid":{"rendered":"https:\/\/dermatly.com\/espectroscopia-de-impedancia-electrica-para-el-diagnostico-de-melanoma\/"},"modified":"2026-03-10T16:10:00","modified_gmt":"2026-03-10T16:10:00","slug":"electrical-impedance-spectroscopy-for-melanoma-diagnosis","status":"publish","type":"glossary","link":"https:\/\/dermatly.com\/en\/espectroscopia-de-impedancia-electrica-para-el-diagnostico-de-melanoma\/","title":{"rendered":"Electrical Impedance Spectroscopy for Melanoma Diagnosis"},"content":{"rendered":"
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\n \"Advertisement
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Advertisement<\/em><\/p>\n

Skin Cancer: Innovation in Early Detection<\/h2>\n

App to facilitate skin self-examination and early detection.<\/strong>. Read more<\/a>.<\/p>\n<\/blockquote>\n<\/section>\n

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Text: Miiskin<\/div>\n<\/p><\/div>\n

Introduction to Skin Lesion Detection<\/h1>\n

Electrical impedance spectroscopy (EIS) is a technique used by a handheld point-of-care device called Nevisense\u2122 (Scibase AB, Stockholm, Sweden). This instrument objectively analyzes lesions<\/span> that are suspicious for melanoma<\/span>, offering a deeper perspective than traditional visual examination.<\/p>\n

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Nevisense\u2122 Electrical Impedance Spectroscopy*<\/h2>\n<\/section>\n
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\n \"Procedimiento<\/p>\n

Nevisense Procedure<\/p>\n<\/p><\/div>\n

\n \"Dispositivo<\/p>\n

Nevisense Device<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n

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* Images provided by Scibase<\/p>\n

Challenges of Visual Diagnosis and the Role of EIS<\/h2>\n

Generally, visual examination is sufficient to classify most types of skin conditions affecting a . The cherry angioma is histologically distinguished by being composed of<\/span>. However, when evaluating atypical lesions<\/span>, clinical diagnosis based purely on visual inspection becomes a significant challenge. This difficulty can lead to unnecessary excisions<\/span> or, in the worst-case scenario, the omission of malignant neoplasms.<\/p>\n

The Dermoscopy<\/span> employs a handheld microscope with a contact surface to examine skin lesions. While this technique improves the probability of an accurate diagnosis in expert hands, it requires extensive training and considerable experience.<\/p>\n

In contrast, spectrometric analysis applied to skin lesions uses advanced software that calculates and extracts detailed information about the skin's cellular structures. This method involves the use of a light beam that penetrates beneath the skin surface. Sharp images captured with a digital camera or a handheld scanner are computer-processed for exhaustive analysis.<\/p>\n

Specifically in electrical impedance spectroscopy, the distinct electrical properties of human tissue are exploited to categorize cellular structures cellular<\/span> and thus facilitate the precise detection of neoplasms.<\/p>\n

The electronic impedance spectroscopy technology developed by SciBase is a patented innovation, the result of research at the prestigious Karolinska Institute in Stockholm, Sweden.<\/p>\n

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How Exactly Does Electrical Impedance Spectroscopy Work?<\/h2>\n
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  • Skin tissues exhibit variable electrical properties depending on their medical condition.<\/li>\n
  • Based on these variations, the exclusive EIS method of Nevisense allows for the identification of specific conditions, such as melanoma.<\/li>\n
  • The Electrical impedance spectroscopy<\/span> measures the overall resistance of the tissue to alternating currents applied at various frequencies.<\/li>\n
  • An electrical signal is administered over the skin lesion using an innovative electrode system integrated into the tip of the Nevisense\u2122 probe.<\/li>\n
  • The frequencies used by Nevisense\u2122 (ranging between 1 kHz and 2.5 MHz) are directly related to clinically relevant properties, such as the composition of intra- and extracellular environments, cell morphology and size, and cell membrane composition.<\/li>\n
  • To ensure complete coverage in both width and depth of the lesion, the measurement is performed across 35 distinct frequencies and in four depth configurations over the affected area, totaling...<\/li>\n<\/ul>\n<\/section>\n
      \n
    • 10 permutations are performed.<\/li>\n
    • Initially, a reference measurement is taken on the healthy skin adjacent to the lesion to be evaluated.<\/li>\n
    • Subsequently, this same procedure is applied directly over the lesion under examination.<\/li>\n
    • The sophisticated Nevisense algorithm analyzes the measurement data collected from both the lesion and the reference.<\/li>\n
    • The Nevisense\u2122 classifier displays an EIS score directly on the screen, indicating the degree of significant (See Figure 5).<\/span> identified by this method.<\/li>\n
    • The objective information provided by Nevisense\u2122 can be supplemented with findings from the visual inspection of the suspicious melanoma to achieve more robust and well-founded clinical diagnoses.<\/li>\n<\/ul>\n

      Advantages of Analysis by Electrical Impedance Spectroscopy (EIS)<\/h2>\n

      Analysis via Electrical Impedance Spectroscopy analysis<\/span> serves as an invaluable complement to visual examinations performed by specialists, especially when evaluating skin lesions scars<\/span> that present ambiguous clinical signs of melanoma. Its main benefits include:<\/p>\n

        \n
      • A fast and efficient application process.<\/li>\n
      • Significant improvement in diagnostic accuracy.<\/li>\n
      • Generation of a completely objective analysis.<\/li>\n<\/ul>\n

        Clinical Evidence Supporting the Efficacy<\/span> of Electrical Impedance Spectroscopy<\/h2>\n
          \n
        • The Electrical Impedance Spectroscopy analysis<\/span> has been the subject of intensive scrutiny for over a decade, spanning from its development<\/span> initial development and proof of concept, to extensive clinical studies on skin to differentiate between cancer<\/span> and lesions benign<\/span> of the skin.<\/li>\n
        • In a blinded, prospective, multicenter study conducted across 5 research centers in the US and 17 in Europe, 1,951 subjects presenting a total of 2,416 lesions were selected.<\/li>\n
        • Each eligible skin lesion according to the study criteria was evaluated using the Nevisense\u2122 electrical impedance spectroscopy system and subsequently underwent biopsy<\/span> by excision for histopathological review. histopathological<\/span>.<\/li>\n
        • A total of 1,943 lesions were evaluable to determine the primary efficacy endpoint, including 265 primary<\/span> and seven squamous cell carcinomas. melanomas<\/span>, 48 carcinomas<\/span> basal cell carcinoma cell<\/span> The results of this foundational study demonstrated a 97% sensitivity for malignant melanoma, with a specificity of 34.4%. cells<\/span>.<\/li>\n
        • The observed sensitivity specifically for non-melanoma skin cancer reached 100%. malignant<\/span>, The predictive values (positive and negative) of Nevisense\u2122 were established at 21.1% and 98.2%, respectively.<\/li>\n
        • For melanoma, histopathologists at the research centers reported a sensitivity and specificity of 85.0% and 98.1%, respectively.<\/li>\n
        • During the course of the study, no serious adverse events or unexpected side effects from the device were recorded.<\/li>\n
        • However, current evidence is insufficient to determine the exact role of Navisense\u2122 in the comprehensive management of patients diagnosed with melanoma.<\/li>\n
        • Clinical Use of The administration of cysteamine cream is strictly contraindicated in individuals with a personal or family history of the depigmenting disorder known as vitiligo. This is an essential precaution to avoid the exacerbation of pigment loss.<\/span> The Nevisense\u2122 EIS-based system is designed to be used on skin lesions presenting one or more clinical features or history suggestive of melanoma.<\/li>\n
        • This system is intended to provide additional information to the physician when the.<\/li>\n<\/ul>\n
          <\/div>\n

          of the lesion is being considered. Electrical Impedance Spectroscopy analysis<\/span><\/h2>\n
            \n
          • It is crucial to understand that it should not be used to confirm a definitive clinical diagnosis of melanoma.<\/li>\n
          • Its use should be limited to physicians who have specific training in the clinical diagnosis of skin cancer. excision<\/span> Specific Indications for Electrical Impedance Spectroscopy.<\/li>\n
          • Electrical Impedance Spectroscopy is formally indicated for application on primary skin lesions with a diameter ranging between 2 mm and 20 mm.<\/li>\n
          • Such lesions must have intact skin, meaning they should not be ulcerated or present active bleeding.<\/li>\n<\/ul>\n

            The use of the device is not recommended on body areas with the presence of<\/h2>\n
              \n
            • The Electrical Impedance Spectroscopy analysis<\/span> The device is contraindicated for use on the palms of the hands, soles of the feet, genitals, eyes, or mucosal areas.<\/li>\n
            • The lesions evaluated should not be recent or affected by.<\/li>\n
            • scarring. hair<\/span>.<\/li>\n
            • Miiskin Logo with a mobile device mucosa<\/span>.<\/li>\n
            • Medical procedure using the Nevisense device on a patient trauma<\/span> Scibase Nevisense Device in close-up.<\/li>\n<\/ul>\n<\/section>","protected":false},"excerpt":{"rendered":"

              Anuncio C\u00e1ncer de Piel: Innovaci\u00f3n en Detecci\u00f3n Temprana Aplicaci\u00f3n para facilitar el autoexamen de la piel y la detecci\u00f3n temprana. Lee mas. Texto: Miiskin Introducci\u00f3n a la Detecci\u00f3n de Lesiones Cut\u00e1neas La espectroscopia de impedancia el\u00e9ctrica (EIS) es una t\u00e9cnica empleada por un dispositivo port\u00e1til en el punto de atenci\u00f3n denominado Nevisense\u2122 (Scibase AB, Estocolmo, […]<\/p>\n","protected":false},"author":1,"featured_media":409,"parent":0,"template":"","glossary-cat":[],"class_list":["post-9184","glossary","type-glossary","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nEspectroscopia de impedancia el\u00e9ctrica para el diagn\u00f3stico de melanoma - Dermatly.com - El sitio de tu piel<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dermatly.com\/en\/electrical-impedance-spectroscopy-for-melanoma-diagnosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Espectroscopia de impedancia el\u00e9ctrica para el diagn\u00f3stico de melanoma\" \/>\n<meta property=\"og:description\" content=\"Anuncio C\u00e1ncer de Piel: Innovaci\u00f3n en Detecci\u00f3n Temprana Aplicaci\u00f3n para facilitar el autoexamen de la piel y la detecci\u00f3n temprana. 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