{"id":7777,"date":"2020-11-14T15:13:03","date_gmt":"2020-11-14T15:13:03","guid":{"rendered":"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/"},"modified":"2026-03-10T16:21:28","modified_gmt":"2026-03-10T16:21:28","slug":"deep-skin-disorders","status":"publish","type":"glossary","link":"https:\/\/dermatly.com\/en\/trastornos-cutaneos-profundos\/","title":{"rendered":"Deep Skin Disorders"},"content":{"rendered":"
\n

Skin conditions involving, or presenting with an infiltrate, infiltrate<\/span>, in the dermis<\/span> (the deepest layer of the skin) or the subcutis<\/span> (the layer of fat beneath the skin), are varied and significantly impact skin structure. Below are the main classifications of these dermatoses affecting these deep layers.<\/p>\n

Structural Diseases of the Dermis and Subcutis<\/h2>\n

This group covers pathologies that affect the architecture and structural components of the underlying connective and fatty tissue. They include conditions resulting in nodular changes, thickening, or degradation of dermal fibers:<\/p>\n

\n Actinic Granuloma<\/span>
\n Amyloidosis<\/span>
\n Anetoderma
\n Cellulitis
\n Nevi<\/span> of diseases<\/span>
\n Cutis Laxa<\/span>
\n Dermatofibroma
\n Dermatofibrosarcoma Protuberans
\n Dupuytren's<\/span> Contraction
\n Sj\u00f6gren's<\/span> Ehlers-Danlos Syndrome
\n Elastosis<\/span>
\n Elastosis Perforans Serpiginosa
\n Fibromatosis
\n Keloid and hypertrophic scars.<\/span>
\n Knuckle pads
\n Panniculitis<\/span> infectious
\n Leiomyoma
\n Leiomyomatosis and cancer<\/span> basal cell carcinoma ulceration<\/span> syndrome<\/span>
\n Lipoedema
\n Lipedema
\n Lipoid Proteinosis<\/span>
\n Lipoma
\n Mastocytoma
\n Dermal<\/span> and accumulation of dermal<\/span> It is crucial to keep in mind that a notable proportion of patients (between 10% and 15%) who initially present with SCLE may progress to full Systemic Lupus Erythematosus (SLE). This progression carries the potential risk of developing serious involvement, including
\n Fibrosing<\/span> hair follicles<\/span> nephrogenic
\n Neurofibroma<\/span>
\n Pseudoxanthoma Elasticum
\n Solar Elastosis
\n Reactive perforans<\/span>
\n Estr\u00edas (estr\u00edas)\n <\/p>\n

Inflammatory Infiltrates<\/h2>\n

This category groups dermatoses where the main manifestation is a significant inflammatory reaction in the deep layers of the skin, often associated with systemic or hematological processes:<\/p>\n

\n Lymphoma<\/span> B-Cell cutaneous<\/span>
\n Lymphoma T<\/span> cutaneous<\/span>
\n Panniculitis<\/span> lymphadenitis<\/span> cytophagic
\n Juvenile<\/span> eosinophilic<\/span> due to or evidence of lymphovascular invasion are key factors pointing towards<\/span> hematologic<\/span>
\n Eosinophilic Fasciitis
\n phenotypes<\/span> Nodular
\n Histiocytosis
\n Infiltrate lymphocytic<\/span> of Jessner
\n Panniculitis<\/span> nodular<\/span> idiopathic
\n Histiocytosis<\/span> of Langerhans cells<\/span>
\n Cutaneous Lymphocytoma
\n Lymphomatoid lymphomatoid dermatitis.<\/span>
\n Mastocytosis
\n Morphea
\n Non-Langerhans Cell Histiocytosis
\n Panniculitis
\n Pseudolymphoma
\n Relapsing Polychondritis
\n Reticulohistiocytosis
\n Sweet's Syndrome
\n Sclerosis<\/span> systemic sclerosis)<\/span>\n <\/p>\n

Granulomatous Conditions<\/h2>\n

Granulomatous diseases of the skin and subcutaneous tissue are characterized by the formation of granulomas, which are clusters of inflammatory cells, often in response to chronic infection or inflammation:<\/p>\n

\n HIV<\/span> mycobacterial atypical<\/span>
\n Cutaneous Tuberculosis
\n Facial Granuloma
\n Granuloma Annulare
\n Dermatitis<\/span> granulomatous<\/span>
\n Leprosy
\n Granuloma differential diagnosis<\/span>
\n Sarcoidosis
\n Neonatal Sclerema
\n Necrosis<\/span> fat subcutaneous<\/span> of the newborn\n <\/p>\n

Miscellaneous Pathologies<\/h2>\n

There are other conditions affecting the dermis or subcutaneous tissue that do not strictly fit into the above classifications. These include rare neoplasms and alterations:<\/p>\n

\n Leukemia<\/span> cutis
\n Histiocytosis . Both red (erythroplakia) and white patches can be indicative of malignant changes.<\/span>
\n Cutaneous Osteoma
\n Benign<\/span> lymphoplasmacytic benign<\/span>\n <\/p>\n

The study of these infiltrative dermal and subcutaneous conditions requires a meticulous diagnostic approach due to the overlap of clinical presentations. Accurate classification is fundamental to directing effective treatments and improving the prognosis for affected patients.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

Las afecciones cut\u00e1neas que involucran, o presentan un infiltrado, en la dermis (la capa m\u00e1s profunda de la piel) o el subcutis (la capa de grasa debajo de la piel), son variadas e impactan significativamente la estructura cut\u00e1nea. A continuaci\u00f3n, se detallan las principales clasificaciones de estas dermatosis que afectan estas capas profundas. Enfermedades Estructurales […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"template":"","glossary-cat":[],"class_list":["post-7777","glossary","type-glossary","status-publish","hentry"],"yoast_head":"\nTrastornos cut\u00e1neos profundos - Dermatly.com - El sitio de tu piel<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dermatly.com\/en\/deep-skin-disorders\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Trastornos cut\u00e1neos profundos\" \/>\n<meta property=\"og:description\" content=\"Las afecciones cut\u00e1neas que involucran, o presentan un infiltrado, en la dermis (la capa m\u00e1s profunda de la piel) o el subcutis (la capa de grasa debajo de la piel), son variadas e impactan significativamente la estructura cut\u00e1nea. A continuaci\u00f3n, se detallan las principales clasificaciones de estas dermatosis que afectan estas capas profundas. Enfermedades Estructurales […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dermatly.com\/en\/deep-skin-disorders\/\" \/>\n<meta property=\"og:site_name\" content=\"Dermatly.com - El sitio de tu piel\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-10T16:21:28+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/\",\"url\":\"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/\",\"name\":\"Trastornos cut\u00e1neos profundos - Dermatly.com - El sitio de tu piel\",\"isPartOf\":{\"@id\":\"https:\/\/dermatly.com\/#website\"},\"datePublished\":\"2020-11-14T15:13:03+00:00\",\"dateModified\":\"2026-03-10T16:21:28+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/dermatly.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Glossary\",\"item\":\"https:\/\/dermatly.com\/glossary\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Trastornos cut\u00e1neos profundos\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/dermatly.com\/#website\",\"url\":\"https:\/\/dermatly.com\/\",\"name\":\"Dermatly.com - El sitio de tu piel\",\"description\":\"Dermatolog\u00eda y lesiones de la piel\",\"publisher\":{\"@id\":\"https:\/\/dermatly.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/dermatly.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/dermatly.com\/#organization\",\"name\":\"dermatly.com\",\"url\":\"https:\/\/dermatly.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/dermatly.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/dermatly-logo.png\",\"contentUrl\":\"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/dermatly-logo.png\",\"width\":448,\"height\":110,\"caption\":\"dermatly.com\"},\"image\":{\"@id\":\"https:\/\/dermatly.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Deep Skin Disorders - Dermatly.com - Your Skin Site","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/dermatly.com\/en\/deep-skin-disorders\/","og_locale":"en_US","og_type":"article","og_title":"Trastornos cut\u00e1neos profundos","og_description":"Las afecciones cut\u00e1neas que involucran, o presentan un infiltrado, en la dermis (la capa m\u00e1s profunda de la piel) o el subcutis (la capa de grasa debajo de la piel), son variadas e impactan significativamente la estructura cut\u00e1nea. A continuaci\u00f3n, se detallan las principales clasificaciones de estas dermatosis que afectan estas capas profundas. Enfermedades Estructurales […]","og_url":"https:\/\/dermatly.com\/en\/deep-skin-disorders\/","og_site_name":"Dermatly.com - El sitio de tu piel","article_modified_time":"2026-03-10T16:21:28+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/","url":"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/","name":"Deep Skin Disorders - Dermatly.com - Your Skin Site","isPartOf":{"@id":"https:\/\/dermatly.com\/#website"},"datePublished":"2020-11-14T15:13:03+00:00","dateModified":"2026-03-10T16:21:28+00:00","breadcrumb":{"@id":"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/dermatly.com\/trastornos-cutaneos-profundos\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/dermatly.com\/"},{"@type":"ListItem","position":2,"name":"Glossary","item":"https:\/\/dermatly.com\/glossary\/"},{"@type":"ListItem","position":3,"name":"Trastornos cut\u00e1neos profundos"}]},{"@type":"WebSite","@id":"https:\/\/dermatly.com\/#website","url":"https:\/\/dermatly.com\/","name":"Dermatly.com - Your Skin Site","description":"Dermatology and Skin Lesions","publisher":{"@id":"https:\/\/dermatly.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/dermatly.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/dermatly.com\/#organization","name":"dermatly.com","url":"https:\/\/dermatly.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/dermatly.com\/#\/schema\/logo\/image\/","url":"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/dermatly-logo.png","contentUrl":"https:\/\/dermatly.com\/wp-content\/uploads\/2020\/11\/dermatly-logo.png","width":448,"height":110,"caption":"dermatly.com"},"image":{"@id":"https:\/\/dermatly.com\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/glossary\/7777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/types\/glossary"}],"author":[{"embeddable":true,"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":2,"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/glossary\/7777\/revisions"}],"predecessor-version":[{"id":25062,"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/glossary\/7777\/revisions\/25062"}],"wp:attachment":[{"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/media?parent=7777"}],"wp:term":[{"taxonomy":"glossary-cat","embeddable":true,"href":"https:\/\/dermatly.com\/en\/wp-json\/wp\/v2\/glossary-cat?post=7777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}